What clinical feature distinguishes nodular melanoma from other types?

Nodular melanoma is characterized by its raised, dark lesions, which significantly distinguish it from other types of melanoma. This vertical growth pattern leads to a more pronounced elevation compared to other melanoma types, which may present as flat lesions. The pigmentation in nodular melanoma often appears dark, frequently with an even distribution of color but can also show variations. However, the key feature remains the raised, dome-shaped appearance that develops early in its course.

While asymmetrical shape and irregular borders can be seen in various melanomas, including nodular melanoma, they are not exclusive to it. A uniform color is less characteristic of melanoma overall, as these lesions, including nodular melanoma, often are noted for their variability in pigmentation. Therefore, the distinctive raised nature of the lesion in nodular melanoma is what sets it apart from other forms of melanoma, making "raised, dark lesion" the correct distinguishing feature.