What is a common side effect of isotretinoin therapy?

Isotretinoin therapy is widely recognized for its effectiveness in treating severe acne, but it is also known for its side effects. One of the most common and notable side effects is the drying of the skin and mucous membranes. This occurs because isotretinoin significantly reduces sebum production, leading to a decrease in the skin's natural oils. The skin can become excessively dry, which may result in flaking, redness, and overall sensitivity. Additionally, mucous membranes such as those in the mouth and eyes may also become dry, leading to discomfort and other related issues.

Other potential side effects of isotretinoin include changes to lipid levels and potential mood alterations, but the drying effects are universally acknowledged among patients undergoing treatment. This side effect leads to a recommendation for regular moisturization and the use of lip balms during the course of treatment to alleviate discomfort.

In contrast, increased hair growth, hyperpigmentation, and oily skin are not typical side effects associated with isotretinoin therapy, as the medication primarily targets the mechanisms that cause excess oil production. Consequently, these other symptoms are less likely to be observed in individuals taking this medication.