What is the common presentation of erythema infectiosum?

Erythema infectiosum, commonly known as fifth disease, typically presents with a distinctive "slapped cheek" appearance, particularly in children. This characteristic rash usually begins with bright red cheeks that appear as though the child has been slapped, which is a hallmark feature of the condition. Following the appearance of the facial rash, it often progresses to a lacy, reticular pattern on the trunk and extremities.

This presentation is associated with infection by parvovirus B19, which affects primarily children, though adults can also present with non-specific symptoms such as mild arthralgia. Recognizing the "slapped cheek" appearance is essential for diagnosis, as it helps to distinguish erythema infectiosum from other childhood rashes.

The other choices represent different dermatological conditions that do not apply to erythema infectiosum: pruritic vesicles would suggest chickenpox or herpes simplex infections; diffuse pustular lesions might indicate conditions such as bacterial infections or pustular psoriasis; and yellow crusted lesions are typically associated with impetigo or other forms of superficial bacterial skin infection. Thus, the "slapped cheek" appearance is a defining and recognizable feature specific to erythema infectiosum.