What type of skin cancer is associated with exposure to arsenic?

Prepare for the Dermatology PANCE with flashcards and multiple-choice questions. Each question includes hints and detailed explanations. Get exam-ready!

Squamous cell carcinoma is indeed associated with exposure to arsenic, making it the correct choice. Arsenic is a well-known carcinogen that increases the risk of developing various skin conditions, particularly squamous cell carcinoma. This type of cancer typically arises from the keratinocytes in the epidermis and is linked to various environmental and occupational exposures, with arsenic being a significant risk factor.

The connection between arsenic exposure and squamous cell carcinoma can be attributed to the compound's ability to promote cellular mutations and interfere with normal cellular processes, leading to uncontrolled growth and malignancy. Chronic exposure to arsenic, especially through drinking water in certain regions, can lead to skin manifestations and ultimately result in the development of squamous cell carcinoma.

In contrast, basal cell carcinoma is primarily associated with ultraviolet (UV) radiation exposure and is less commonly linked to arsenic. Melanoma, while also influenced by UV radiation, has different risk factors, including genetic predisposition and existing moles. Actinic keratosis, on the other hand, is a precancerous condition caused predominantly by sun exposure rather than arsenic. Understanding these associations helps in the identification, prevention, and management of skin cancers related to environmental factors.

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